In solving the low bioavailability of poor water soluble drugs self micro emulsifying drug delivery system (SMEDDS) forms the main technique. This system can enable the hydrophobic drugs to dissolve easily in the system by formulating them in to unit dosage forms mainly for per oral administration. When this system is released in the gastrointestinal tract (lumen) it disperses resulting in the fine emulsion with particle size ranging from micro to nano. The pseudo-ternary phase diagrams are drawn to identify the micro emulsion region. The SMEDDS are evaluated for physico-chemical properties, drug release, diffusion and permeation and zeta potential.
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